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Hi,There is not a direct flight to Colombia but you can travel with Iberia, Air France or American Airlines. To get from Cartagena to Santa Marta is very easy. You can actually travel by bus and it usually takes 2 to 3 hours. Cartagena is such a beautiful colonial places you will have a great time there. I recommend you to stay in the old town, as pretty much all the activities are around this area. Also, it is very easy to walk around. Santa Marta has amazing beaches. If you have time I recommend you to visit Tayrona Park (Natural Park). In my opinon is one of the most beautiful places in Colombia. I hope you have a great trip.